This Monongalia County native was one of the state’s most notable artists and is recognized as one of America's leading abstract painters and print makers. Unusually independent for a woman of her time, Lazzell traveled twice to Paris, absorbing the principles of Cubism and studying with such early modernists as Charles Guerin, Fernand Léger, and Albert Gleizes. She's most known as a founding member of the Provincetown Printers, a Massachusetts group that favored single block color prints. From 1916 on, Lazzell worked in this printing method and in other media, including watercolor and oil.

During the Depression, she was commissioned by the Works Progress Administration to create several color wood-block prints of scenes in and around Morgantown and a mural for the courthouse titled "Justice over Monongalia County."