On July 1, 1942, a troop transport plane crashed in McDowell County, killing 21 Army Air Corps members.

On April 14, 1945, a commercial plane crashed into Cheat Mountain, killing 20 people.

On April 8, 1951, a C-47 plane crashed near Kanawha Airport, killing 21 Air National Guard members on their way to a funeral. The Guard still wears a patch with 21 stars to honor the victims.

On August 10, 1968, a Piedmont Airlines plane crashed near Yeager Airport, killing 35 out of 37 people on board.